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英文名稱 Anti-AADACL4/FITC
中文名稱 FITC標記的芳香乙酰胺脫乙酰基酶樣蛋白4抗體
別 名 Aadacl4; ADCL4_HUMAN; Arylacetamide deacetylase like 4; Arylacetamide deacetylase-like 4.   
說 明 書 100ug  
研究領域 腫瘤  心血管  細胞生物  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Rabbit, 
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
細胞定位 細胞膜 
性 狀 Lyophilized or Liquid
濃 度 2mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human AADACL4 (334-380aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Subcellular Location:
Membrane; Single-pass type II membrane protein

Similarity:
Belongs to the 'GDXG' lipolytic enzyme family.

Database links:
UniProtKB/Swiss-Prot: Q5VUY2.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.