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武漢紐斯特生物科技有限公司
武漢紐斯特生物科技有限公司
Rab35ProteinQ67Lmutant[10133][25µg]CatalogNumber:10133ProductName:Rab35ProteinQ67LmutantSynonyms:MemberRASoncogenefamily
Rab35 Protein Q67L mutant [10133]
[25 µg]
| Catalog Number: 10133 |
| Product Name: Rab35 Protein Q67L mutant |
| Synonyms: Member RAS oncogene family, RAY, H-ray, RAB1C |
| Source: Human, recombinant full length, His6-tag |
| Expression Host: E. coli |
| Molecular Weight: 23 kDa |
| Purity: >95% by SDS-PAGE |
| Introduction: The Ras super-family of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, the Rab family appears to play a critical role in regulating exocytotic and endocytotic pathways. RAB35 regulates the assembly of actin filaments during bristle development in Drosophila and filopodia formation in cultured cells. |
| Amino Acid Sequence (1-201, Q67L) |
| MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGL ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETED AYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC |
| Properties |
| Physical Appearance (form): Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl. |
| Physical Appearance (form): White or clear |
| Concentration: 1 mg/mL |
| Storage: -80°C |
| Preparation Instructions: Centrifuge the vial before open the cap and reconstitute in water. Adding of 10 mM β-mercaptoethanol or 1 mM DTT into the solution to protect the protein is recommended and using of non-ionic detergents such as n-Dodecyl β-D-maltoside (DoDM) or polyethylene detergents (e.g. C12E10) also help to stabilize the protein. Avoid repeated freezing and thawing after reconstitution. The purity of His-tagged Rab35 QL was determined by SDS-PAGE and Coomassie Brilliant Blue Staining. |
| References: 1. Zhang, J. et al., Science 325: 1250-1254, 2009. 2. Zhu, A. X. et al., Biochem. Biophys. Res. Commun. 205: 1875-1882, 1994. |
| Datasheet: |
| Related Products | |||
| Catalog# | Name | Size | Price |
| Rab35 Activation Assay Kit | 20 assays | ￥6800 | |
| Active Rab35-GTP Monoclonal Antibody | 30 μL | ￥4800 | |
| Anti-Rab35 Rabbit Polyclonal Antibody | 100 μL | ￥2600 | |
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