抗細胞凋亡蛋白OLFM44抗體,Anti-OLFM4抗體實驗說明*,在上海研盟生物,我們堅持對產品質量作不斷的評估、創新和改善以確保您對我們產品的高度信任!抗體應用于WB、IHC、IF、ELISA等實驗中,*,提供完善的售前、售中、售后服務!咨詢或在線客服!我們將竭誠為您服務!
背景介紹:Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein which contains one olfactomedin-like domain. OLFM4 is expressed during myeloid lineage development. It is strongly expressed in the prostate, small intestine and colon and moderay expressed in the bone marrow and stomach. OLFM4 is highly expressed in pancreatic cancer tissues and shows an elevated expression level during the early S phase of the cell cycle. It is also expressed at high levels in stomach cancer and colon cancer tissues. Inhibition of ROS or the ERK pathway remarkably decreased G-CSF-induced OLFM4 expression. OLFM4 is an antiapoptotic factor that promotes tumor growth. OLFM4 promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. OLFM4 also facilitates cell adhesion. Induction of OLFM4 in cancer cells was reported to have a novel antiapoptotic action via binding to the potent apoptosis inducer GRIM-19. The human OLFM4 is also thought to be a useful marker for early myeloid development.
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英文名稱 OLFM4
抗體名稱 抗細胞凋亡蛋白OLFM44抗體,Anti-OLFM4抗體實驗說明
別 名 Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; GC1; GW112; hGC 1; hGC-1; hOLfD; olfactomedin 4; Olfactomedin-4; OlfD; OLFM4; OLFM4_HUMAN; OLM4.
研究領域 腫瘤 腫瘤細胞生物標志物
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
產品應用 WB=1:100-500 ELISA=1:500-1000 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細胞定位 細胞漿 細胞膜 細胞外基質 分泌型蛋白
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human OLFM4
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
本公司另供應“抗細胞凋亡蛋白OLFM44抗體”的標記有:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC.
產品規格:100ug/200ug
產品濃度: 1mg/1ml
抗體來源:兔源、鼠源、山羊
克 ?。簡慰寺】贵w、多克隆抗體
抗體類型:一抗
性 狀: 凍干粉或液體
保存條件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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