Mouse Anti-G-CSF抗體 antibody
FROM:ricky
Catalog Number : Rs-1023r
Quantity size :0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
Subunit:
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine
belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell
proliferation and differentiation. G-CSF was isolated initially as a factor supporting the
growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage
lineage are among the most prominent sources of G-CSF, but this factor can also be produced
by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and
mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety
of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is
likely to play a role in the basal regulation of neutrophil production, and also functions as a
primary regulatory factor controlling the neutrophil response to inflammatory stimuli.
Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since
G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the
body.
Specificity :
–Anti-G-CSF is a mouse monoclonal antibody.
– specific for G-CSF antibody of Human, Mouse, Rat, Pig, Cow, Sheep,
– use for western blotting, elisa, immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt : 19 kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
The lyophilized antibody is stable at room temperature for at least one month and for
greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M
PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃.
Important Note: This product as supplied is intended for research use only, not for
use in human, therapeutic or diagnostic applications.
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